Preheat oven to 350°F. Grease and flour two 9x5-inch loaf pans.

### Make the filling:

In a medium bowl with an electric hand mixer, beat the cream cheese, egg, vanilla, and brown sugar on medium speed until well combined. Do not worry if there are still some small lumps of cream cheese. Set aside.

### Make the streusel topping:

In a medium bowl, stir together the brown sugar, flour, pumpkin pie spice, and salt. Add the melted butter and mix with a fork until the mixture is well combined and forms clumps. Place the bowl in the refrigerator until ready to use.

### Make the bread:

In the bowl of a stand mixer fitted with the paddle attachment or in a large bowl with an electric mixer, combine pumpkin, eggs, oil, water, vanilla and sugar until well blended.

In a large bowl, whisk together the flour, baking soda, salt, and pumpkin pie spice until combined.

Stir the dry ingredients into the pumpkin mixture until just blended.

Add ¼ of the batter into the bottom of each of the prepared pans. Divide the cream cheese filling between the two pans, spreading over the top of the batter. Spoon the remaining batter over the cream cheese filling, dividing it evenly between the two pans.

Sprinkle the streusel topping evenly over the top of the two loaves.

Bake in preheated oven for 60-70 minutes or until a toothpick inserted in the center comes out clean.